The next INFORM trial is almost completely irrelevent inre IFN since it treats all patients after 28 days with SOC. The interesting trial will be the subsequent phase of trials, which are slated to start in second half 2010 and will be a comparison of ETR and SVR for all oral cocktails vs combos with SOC.

I'd fully expect the RVR comparison to make SOC look pathetic. But the real interesting data is going to be the ETR/SVR data - where I expect phenominal ETR rate (95+ pct) and an equally phenominal relapse rate (say 30+ pct in 24 weeks and 45+ pct over, say, 2 years). But note that this guess of mine is just that - a guess, based upon the fact that to date we have not yet cured ANY chronic viral infection without specifically and intentionally manipulating the immune system. Even AIDS, which has boatloads more money thrown at it, has only seen hints of preventing relapse after anti-viral cocktail - and then only by manipulating the immune system.