Label changes means nothing, being able to detect the jv virus which causes pml is the key for growth of Ty without concern.. With this test to identify those patients who are at risk for pml and making sure they are monitored thru the touch program is very important. The best would be to find a cure for the jv virus,detection is the start. The hf will down play this label change as not important and say there will be a rash of new pml cases.. This just might be sell the news, we will see..The test would shut them up for good..LOL Expansion of Ty into the crohns market will be significant when the test is released by years end.. That is the news I want to see..THE TED YEDNOCK TEST. If all these concerns are met, then biib and eln could push Ty as first line treatment for MS and Crohns and possibly for other immune system disorders. Safety and perception is our biggest concerns and we are headed in the right direction.